Unfortunately, the number of deaths related to opioid overdose has been increasing over the past few decades, and the COVID-19 pandemic has further exacerbated this public health crisis. Therefore, many scientists, healthcare professionals, and government officials have been working tirelessly to end this deadly epidemic. Researchers at the University of Washington are such a group. They recently launched a wearable device that can detect opioid overdose and provide real-time antidote to restore normal body functions.

As the researchers describe in their paper, an overdose of opioids can cause a decrease in respiratory rate, which can lead to hypoxia (lack of oxygen in the blood) and eventually death. Fortunately, the use of naloxone can easily reverse the overdose of opioids. Naloxone is a compound that binds to receptors in the brain. It beats the opioid itself in the competition and restores normal breathing. Unfortunately, if someone takes an overdose, they will not be able to take the antidote on their own, and many opioid overdose occur when the victim is alone (51.8%), so it is necessary to develop an automated system to provide when an overdose is detected Antidote.

The researchers first described their process of measuring respiration. There were several options. You can use photoplethysmography just like measuring your heart rate. Or, you can measure the changes in the impedance of the chest cavity during breathing, or even use intraoral sensors to measure the airflow in the oral cavity. Instead, the researchers chose to measure breathing by connecting an accelerometer to the patient's abdomen and measuring the movement of the abdominal cavity during breathing. They admit that when the patient is not standing still, their technique will be problematic, but think that in the case of an overdose, the patient may be immobilized, and the device will be able to easily measure breathing. They tested their device on dozens of healthy human volunteers and even some opiate users themselves, and showed that their technique fits well with the reference breathing belt placed on the volunteers’ chest.

The cool part of this paper is that they demonstrated a "closed loop" feedback system in which their device measures breathing, detects respiratory arrest (indicating overdose), and provides an antidote. To deliver naloxone, they used an existing commercially available drug delivery system, which requires the user to manually activate the device by pressing a button. They made some modifications to the equipment so that when an opioid overdose is detected, a properly positioned servo motor can be used to activate the trigger to press the button. They simulated an overdose by asking healthy human volunteers to hold their breath for more than 15 seconds. They were able to successfully provide an antidote to 100% of the volunteer team, which shows that the device may work in a real environment.

Now, in order to deploy the device to the field, the appearance of the device undoubtedly needs to be improved, but we believe that these improvements are in progress, and patients have expressed their willingness to wear such devices. In addition, because some drugs can cause seizures in excess, there are still some doubts about whether accelerometer-based breath detection is the best option. Nonetheless, this is an important step in combating the alarming increase in deaths related to opioid overdose, and we hope to see more progress in patient monitoring technology in this area.

I mean, from our point of view, it sounds great... but...

But I am a volunteer for Acid Rescue and Underground Switchboard Suicide and Substance Abuse Hotline 271-3123 through ST. Mary's Hosp Milw went back to when I was a teenager, in the United States when I was in my 20s. Milway. The hospital that supports this has provided a doctor Dr. Alan Reid at every concert,

Pink Floyd PIGS concert MILW...I found a woman giving birth on a baseball field...Sell her to see a doctor...Go back and scan the area I specified...But A glance to monitor the birth...

PPL is stupid about drugs and their situation... Let the events of the day override common sense... Need more volunteers to provide emergency assistance, because in such a stressful period, the responsible party will be Disabled by a short-term event.

I participated in more than 80 concerts. I care about you very much.

My work...cause my dad to hate me. But no matter what Dad thinks, this is a good trade-off. Mom understands. She is a registered nurse.

"Pink Floyd PIGS concert MILW..."-what? "Found a woman giving birth on a baseball field"-what does this matter have to do with the article? "Swept back to monitor the birth..."-Who took what? "My work...cause my dad to hate me."-Why?

Use fewer ellipsis and more words to describe what you mean. Don't get me wrong, I want to know what you are talking about, but you need to improve your way of communication.

What point of view do you want to express?

To quote TFA "...many opioid overdose occurs when the victim is alone (51.8%)".

Maybe this is the fundamental problem. If the victim is "not so lonely" in the beginning, maybe they will reduce their dependence on opioids.

What I mean is: I like every gadget that can save lives (or even make them braver). But we tech geeks should keep a broader view of the problem space. Especially when our PHB tells us not to do this.

Being alone is not a problem in itself. People keep telling you that when you are incomplete, you are incomplete.

I disagree. Humans are social animals, just like wolves and various other animals. This is not just a cultural matter. I'm sure that some people can thrive in isolation, but most people cannot.

One of the behaviors that we drug addicts exhibit is to use the drug of our choice alone. Of course, we can also do it with others around us, but almost all of us will do it without anyone being present and knowing.

Addiction changes the structure of the brain.

When people are so addicted to their drugs, they usually stay away from their friends and family. They themselves will become high or drunk or anything else. This is when OD is most deadly.

After I received the treatment myself, I learned this directly and indirectly through counselors and other addicts who were recovering.

This may be of great help in reducing injuries.

It won’t be because the people who need it are addicts who have exhausted all their money to get drugs. The long-term strategy is not in the driver's cab of drug addicts.

Do you think Tom Petty lacks funds? An addict is not necessarily a homeless needle addict. Most drug addicts develop the habit prescribed by doctors.

are you kidding me? Why do you want to make it easier and more "safe" for people to use these terrible, life-destroying drugs? This will only create more drug addicts. Take this down, hackaday, you are disgusting. This is discouraged. For Pete. shame on you.

Found a poster that didn't understand addiction.

Unless the alleged victim is forced to take opioids, this is voluntary. In this day and age, "not knowing" is a bad excuse. In fact, anyone in a first world country can ask the greatest information service ever-the Internet-about the dangers of opioids. How severe the addiction will be. How addictive. It will destroy and may even kill you. Where to go for treatment. Everything is there, but...Ignorance is bliss.

Although I do support the legalization of certain substances based on their actual effects, opioids and methamphetamine are not among them. These have repeatedly proved their destructiveness to society.

Opioids are legal and have been used in most countries in the Western world. When your doctor prescribes painkillers for your whipping injury, do you think this is the voluntary start of a lifelong addiction?

The proportion of opioid addicts who started using legal illicit drugs is very small. (At least in the UK; if the states are different, you need to sort out your medical system, because there should not be a large number of people getting addicted through medical channels).

But I question how useful this device is to them-it is too addictive for them to ensure that this device is set up correctly. If there are resources to properly allocate and use these drugs, let us use these manpower to provide people with the help they need to get rid of drugs. Devices like this need to operate reliably for months, without maintenance or adjustment, and without battery replacement. And accept abuse on the street.

You might try to attract people who come to buy methadone-ask the pharmacist to check if it is set up correctly-but I think most addicts don't care much by then.

Fundamentally, this does not solve the problem. Addicts who die from drug overdose are not a problem. The problem is what caused them to end up taking drugs.

In the United States, there is a huge "moral" argument that people should not be exposed to drugs or even be told about the effects of drugs. "Don't tell your children the benefits and disadvantages of opioids, it may make them addicted!" Not a rare expression.

If children do use the Internet to "do their own research", they will eventually use tiktok, facebook and other "learning" models and expose them to more drug media. Of course, places like Erowid will say good or bad. But the children are not very good at the risk/reward balance.

As a child who had undergone several operations before the age of 10, I was exposed to a lot of painkillers, benzo and barbiturate sedatives, etc. I know how they feel, and I know the good and bad they might bring. Friends will ask about them, but when the school does a "drug awareness" thing, no one can talk; I can't even say aloud "No, the medicine is bad because..."

The Puritan system in the United States helps to cause the worst effects of addiction. Harm reduction and education can reduce deaths, but "drug users must be punished" and similar mentalities make the problem worse, not better.

Not everyone is as rich or conscious as you or me. Travel to the city, which will open your eyes. Many people start to take drugs because they are very dissatisfied with their lives, or they have fallen into the abyss of despair. In some ways, this is a way to kill yourself very slowly.

Harm reduction will first discuss ROA, effectiveness, safety issues, and ultimately try to prevent people from using these drugs. Before I did something very stupid(TM), I was vaguely active in the drug sub-community in this larger community. I separated and read Erowid (out of curiosity)-so I already knew the dangers and how to ensure safety . Even so, I have had two accidents. Some minor surgery is required first. After the second time, sheer willpower made me give up. People around me don't understand, take it seriously and ignore me. Not as good as they claim or like Christians.

Now, if it is so easy to quit smoking... but I have a good smoking cessation system. Wait for the next delivery of liquid.

But yes, recreational drug use or drug abuse will not help you solve the problem. It will numb you and delay the resolution of the painful problems in their lives.

Safety, everyone, please be compassionate and understanding to your friends.

I think you disagree with the concept of harm reduction is good, but do others believe that this strategy is really offensive to you?

Things like this only work when someone is deeply addicted, so I don’t know how it can lead to more drug abuse. I admit that other harm reduction strategies may be more like a double-edged sword.

The main hazard reduction may lie in understanding the pharmacology, side effects, route of administration of related chemicals and the reasons for not continuing to do these things. If someone intends to do this, the main way to reduce the harm is to ask the nanny to take hallucinogens or even opioids. If users plan to use opioids or SSRIs or tricyclic antidepressants to stop the effects of bad travel, make sure they have naloxone (the pharmacology behind these drug interactions is fascinating).

I think such equipment belongs to secondary injury prevention, just like the police department has a nasal spray naloxone kit to save someone from an accident or a batch of stepped heroin, and there is more fentanyl than actual heroin. .

Personally, I don’t believe that certain places in California are personal places for people to take drugs, but I want to spend money on educating the public. These things will not help you solve your difficulties, they will only make it become It is more difficult and wastes a large part of a person's life to discover this for himself.

The only disgusting thing here is asking for review because you were offended by the post.

Grab yourself. Hysteria is how animals react.

Unfortunately, some people use opioids when they are alone, and it is best to at least provide them with some kind of safety solution. I agree that this should not be the main solution to the opioid epidemic, but the device can also help people survive an overdose.

Look at this with machine learning glasses: Will this device train people to use this device to initiate the number of opioids?

I believe the current problem is the unstable effectiveness of street drugs and combining them with them, only God knows what will kill you.

no way. In addition to the unpleasant overdose, naloxone (Narcan) can also make you feel withdrawal symptoms.

Someone told me that it was very unpleasant to be hit by a narcan (due to falling from a height almost immediately). Based on this, I don’t see anyone deliberately triggering this action.

Now I won't claim to know much about drug addiction, but I suspect that most overdose is unintentional and due to careless or inconsistent efficacy. I suspect that this is usually the case when the exact dose taken by the addict is slightly higher.

Where do I come from? Most crimes in my area, including murder, robbery, sexual assault, and other violent and non-violent crimes, are committed by opioid addicts. Almost everywhere, opioid addiction is a problem among the local population, and this is the case. However, some people comment here trying to justify "addiction" as if these pills squeeze them into the addict’s mouth. "Oh, but my doctor prescribed these medicines for me, it must be no problem!". Have you heard of your own ideas? You cannot defend any addiction. The problem of addiction is a personal problem, and only addicts can overcome it. There are countless examples in this regard, and countless people who have recovered. Some of them gave inspiring speeches in rehabilitation groups. Please do not try to defend any addiction. That's ridiculous. Please don't try to justify any behavior for the result of addiction, you are responsible for your own behavior, your addiction is not. This is a simple concept of personal responsibility, you have to learn to become a real adult. It is very sad that someone invented this device to make people "feel safer" when taking drugs and make them addicted. What a miserable situation this world is in.

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